Fatores socioeconômicos associados à leptospirose no estadodo Acre, Amazônia ocidental brasileira (2007-2020) / Socioeconomic factors associated with leptospirosis in the stateof Acre, western Brazilian Amazon (2007-2020)

Introdução: doença provocada por infecção de origem bacteriana, a leptospirose é um dos agravos mais negligenciados no Brasil, estando associada a características socioeconômicas. Objetivo: analisar possíveis associações entre taxas de incidência da doença e fatores socioeconômicos no estado do Acre, a partir de análises espaciais. Material e Método: estudo ecológico com uso de dados secundários, sendo feita análise de autocorrelação espacial pelo Índice de Moran Local Bivariado, entre variáveis socioeconômicas e taxa média de incidência de leptospirose de todo o período de estudo. Adicionalmente, a análise espaçotemporal foi desenvolvida por meio de varredura cilíndrica estatística de Kulldorff, com raio de 70 quilômetros e distribuição de probabilidade de Poisson. Resultados: a maior quantidade de casos foi observada em homens, pardos e na faixa etária de 20 a 39 anos, em ambiente domiciliar e em pessoas com ensino fundamental 1 e 2 incompletos. Conclusão: a partir das análises estatísticas espaciais, destacaram-se municípios das partes norte e sul do estado. Ressalta-se que há possibilidade de subnotificação de casos, o que poderia ser analisado a partir de estudos que coletem dados primários.

Introduction: disease caused by infection of bacterial origin, leptospirosis is one of the most neglected diseases in Brazil, being associated with socioeconomic characteristics. Objective: to analyze possible associations between disease rates and socioeconomic factors in the state of Acre, based on spatial analysis. Material and Method: ecological study using secondary data, with analysis of spatial autocorrelation by the Moran Local Bivariate Index, between socioeconomic variables and mean rate of leptospirosis throughout the study period. Additionally, the space-time analysis was performed using Kulldorff statistical cylindrical sweep, with a radius of 70 kilometers and Poisson probability distribution. Results: the highest number of cases was observed in men, brown and in the age group of 20 to 39 years old, in the home environment and in people with incomplete elementary school 1 and 2. Conclusion: from the spatial statistical analyses, municipalities in the northern and southern parts of the state stood out. It should be noted that there is a possibility of underreporting of cases, which could be analyzed based on studies that collect primary data.

Perfil das notificações de dengue e febre chikungunya em Cabo Frio/Rj, 2014-2019 / Profile of dengue and chikungunya notifications in Cabo Frio/Rj, 2014-2019 / Perfil de las notificaciones de dengue y chikungunya en Cabo Frio/Rj, 2014-2019

Introdução: De acordo com a literatura científica, diagnósticos clínicos diferenciais de arboviroses representam uma dificuldade no que tange à dengue, na medida em que está no Brasil há muitos anos, o que acarreta em ser a arbovirose mais conhecida no país. As notificações de arboviroses se tornaram obrigatórias para inserção no SINAN, possibilitando a construção de perfis demográficos e o cálculo de incidências a partir de informações específicas para estas doenças. No que tange à dengue, a epidemia deste agravo ocorre no país desde 1986, evidenciando falhas na prevenção, relacionadas a aspectos socioeconômicos e ambientais. Objetivo: analisar perfis das notificações de dengue e febre de chikungunya dos casos notificados no município de Cabo Frio. Metodologia: Trata-se de estudo transversal e descritivo, com uso de dados secundários do SINAN referentes a casos de arboviroses no município de Cabo Frio/RJ. Foram observadas variáveis relacionadas ao sexo, escolaridade, raça/cor e critérios de confirmação, além do grau de completude. Resultados: Foram notificados 8.777 casos suspeitos de arboviroses, incluindo-se 1.367 notificações (15,57%) referentes à febre de chikungunya e 1.986 (22,63%), à dengue. Em relação ao desfecho, 1186 casos (51,45%) foram fechados como inconclusivos e 344 destes (14,92%) foram descartados como arboviroses. Dentre os inconclusivos, 943 (79,51%) eram referentes à notificação de dengue, idem para os 277 casos descartados (80,52%). Conclusão: Observou-se baixa taxa de completude nas fichas de notificação, explicada pelo baixo número de recursos humanos e pela insuficiente infraestrutura. Sugere-se a interação de diferentes profissionais e pesquisadores, facilitando a compreensão da complexa dinâmica das arboviroses em questão.

Introduction: According to the scientific literature, differential clinical diagnoses of arboviruses represent a difficulty with regard to dengue, as it has been present in Brazil for many years, which makes it the most well-known arbovirus in the country. Notifications of arboviruses became mandatory for inclusion in SINAN, enabling the construction of demographic profiles and the calculation of incidences based on specific information for these diseases. With regard to dengue, the epidemic of this disease has occurred in the country since 1986, showing failures in prevention, related to socioeconomic and environmental aspects. Objective: to analyze profiles of notifications of dengue and chikungunya fever of cases notified in the municipality of Cabo Frio. Methodology: This is a cross-sectional and descriptive study, using secondary data from SINAN regarding cases of arboviruses in the municipality of Cabo Frio/RJ. Variables related to sex, education, race/color and confirmation criteria were observed, in addition to the degree of completeness. Results: 8,777 suspected cases of arboviruses were reported, including 1,367 reports (15.57%) referring to chikungunya fever and 1,986 (22.63%) to dengue fever. Regarding the outcome, 1186 cases (51.45%) were closed as inconclusive and 344 of these (14.92%) were discarded as arboviruses. Among the inconclusive ones, 943 (79.51%) were related to dengue notification, the same for the 277 discarded cases (80.52%). Conclusion: A low completeness rate was observed in the notification forms, explained by the low number of human resources and insufficient infrastructure. It is suggested the interaction of different professionals and researchers, facilitating the understanding of the complex dynamics of the arboviruses in question.

Introducción: Según la literatura científica, los diagnósticos clínicos diferenciales de los arbovirus representan una dificultad con respecto al dengue, ya que está presente en Brasil desde hace muchos años, lo que lo convierte en el arbovirus más conocido en el país. Las notificaciones de arbovirus pasaron a ser obligatorias para su inclusión en el SINAN, lo que permitió la construcción de perfiles demográficos y el cálculo de incidencias a partir de información específica de estas enfermedades. Con respecto al dengue, la epidemia de esta enfermedad se presenta en el país desde 1986, mostrando fallas en la prevención, relacionadas con aspectos socioeconómicos y ambientales. Objetivo: analizar perfiles de notificaciones de dengue y fiebre chikungunya de los casos notificados en el municipio de Cabo Frio. Metodología: Se trata de un estudio transversal y descriptivo, utilizando datos secundarios del SINAN sobre casos de arbovirus en el municipio de Cabo Frio/RJ. Se observaron variables relacionadas con el sexo, escolaridad, raza/color y criterios de confirmación, además del grado de completitud. Resultados: se notificaron 8.777 casos sospechosos de arbovirus, de los cuales 1.367 (15,57%) se referían a fiebre chikungunya y 1.986 (22,63%) a dengue. En cuanto al resultado, 1186 casos (51,45%) se cerraron como no concluyentes y 344 de estos (14,92%) se descartaron como arbovirus. Entre los inconclusos, 943 (79,51%) estaban relacionados con la notificación de dengue, lo mismo para los 277 casos descartados (80,52%). Conclusión: Se observó un bajo índice de completitud en los formularios de notificación, explicado por el bajo número de recursos humanos y la infraestructura insuficiente. Se sugiere la interacción de diferentes profesionales e investigadores, facilitando la comprensión de la compleja dinámica de los arbovirus en cuestión.

Severe acute respiratory syndrome and COVID-19 under the hierarchy of the urban network of municipalities in the state of Acre, western Brazilian Amazon region, 2020-2021: a cross-sectional study

ABSTRACT BACKGROUND: The Respiratory Syndromes Surveillance System was created by the Brazilian Ministry of Health in 2000 to monitor influenza in this country. With the emergence of the new coronavirus pandemic, it became incorporated into the surveillance network for influenza and other respiratory viruses. OBJECTIVE: To analyze the transmission of coronavirus disease 2019 (COVID-19) and severe acute respiratory syndrome (SARS) in the state of Acre through its hierarchical urban network. DESIGN AND SETTING: Cross-sectional, descriptive and ecological study, using a spatiotemporal approach and using secondary data. This study was conducted in the state of Acre, northern Brazil. METHODS: This study used secondary data, and epidemiological weeks and municipalities were taken to be the units of analysis. Incidence rates and kernel intensities were calculated for four study periods. Spatiotemporal analysis was performed using scan statistics to identify clusters of SARS cases and considering the population of each municipality. RESULTS: In general, it could be observed that there were higher kernel rates and intensities in municipalities located in the north and south of this state (i.e. its most populous municipalities). CONCLUSION: Priority areas for interventions to control transmission of COVID-19 were highlighted, with the aim of reducing the risks of transmission to more distant areas in the urban hierarchy of the state of Acre.

Identification of spatial patterns in the distribution of meningitis in the State of Mato Grosso ­ Brazil, from 2007 to 2019 / Identificação de padrões espaciais na distribuição da meningite no estado de Mato Grosso ­ Brasil, no período de 2007 a 2019

Objective: to analyze the underreporting of meningitis records in the state of Mato Grosso, under conditions of vulnerability, based on spatial analysis. Methodology: Meningitis cases and estimated population were collected from DataSUS, organized by municipality of residence in the state of Mato Grosso and year of notification. Incidence rates were calculated by dividing the number of cases by the population, multiplying the result by 100,000. For spatial autocorrelation analysis, mean rates were used for the entire period, in addition to the variables percentage of poor, percentage of the population living in households with toilets and running water, and Municipal Human Development Index ­ Income (MHDI Income), obtained from the Atlas of Human Development in Brazil. Results: in general, inverse autocorrelation was observed for the percentage variable of the population living in households with toilets and running water, with municipalities in the center and southeast of the state under high-high autocorrelation and municipalities in the northwest and northeast under low -low. As for the MHDI Income, cities in the center presented high-high autocorrelation and cities in the south and northwest, low-low. Conclusion: the scenario suggests that there is underreporting of meningitis cases in Mato Grosso, as situations marked by less privileged socioeconomic conditions are risk factors for disease transmission. Improvement of health services is suggested, seeking equitable public policies that aim to reduce the existing inequalities in this country.

Objetivo: analisar a subnotificação dos registros de meningite no estado de Mato Grosso, analisado sob condições de vulnerabilidade, a partir de análise espacial. Metodologia: casos de meningite e população estimada foram coletados no DataSUS, sendo organizados por município de residência no estado de Mato Grosso e ano de notificação. Taxas de incidência foram calculadas a partir da divisão do número de casos pela população, multiplicando o resultado por 100.000. Para análise de autocorrelação espacial, foram utilizadas taxas médias para todo o período, além das variáveis percentual de pobres, percentual da população que vive em domicílios com banheiro e água encanada e Índice de Desenvolvimento Humano Municipal ­ Renda (IDHM Renda), obtidas junto ao Atlas de Desenvolvimento Humano no Brasil. Resultados: de uma forma geral, observou-se autocorrelação inversa quanto à variável percentual da população que vive em domicílios com banheiro e água encanada, com municípios do centro e do sudeste do estado sob autocorrelação alto-alto e municípios do noroeste e do nordeste, sob baixo-baixo. Quanto ao IDHM Renda, municípios do centro apresentaram autocorrelação alto-alto e municípios do sul e noroeste, baixo-baixo. Conclusão: o cenário sugere que há subnotificação de casos de meningite em Mato Grosso, pois situações marcadas por condições socioeconômicas menos privilegiadas são fatores de risco para transmissão da doença. Sugere-se aprimoramento de serviços de saúde, buscando políticas públicas equânimes que visem reduzir as desigualdades existentes neste pa

Severe acute respiratory syndrome and COVID-19 under the hierarchy of the urban network of municipalities in the state of Acre, western Brazilian Amazon region, 2020-2021: a cross-sectional study.

BACKGROUND: The Respiratory Syndromes Surveillance System was created by the Brazilian Ministry of Health in 2000 to monitor influenza in this country. With the emergence of the new coronavirus pandemic, it became incorporated into the surveillance network for influenza and other respiratory viruses. OBJECTIVE: To analyze the transmission of coronavirus disease 2019 (COVID-19) and severe acute respiratory syndrome (SARS) in the state of Acre through its hierarchical urban network. DESIGN AND SETTING: Cross-sectional, descriptive and ecological study, using a spatiotemporal approach and using secondary data. This study was conducted in the state of Acre, northern Brazil. METHODS: This study used secondary data, and epidemiological weeks and municipalities were taken to be the units of analysis. Incidence rates and kernel intensities were calculated for four study periods. Spatiotemporal analysis was performed using scan statistics to identify clusters of SARS cases and considering the population of each municipality. RESULTS: In general, it could be observed that there were higher kernel rates and intensities in municipalities located in the north and south of this state (i.e. its most populous municipalities). CONCLUSION: Priority areas for interventions to control transmission of COVID-19 were highlighted, with the aim of reducing the risks of transmission to more distant areas in the urban hierarchy of the state of Acre.

Cancer surveillance in Mato Grosso, Brazil: methodological and operational aspects of a university extension/research project.

OBJECTIVE: To describe the methodological and operational aspects of the "Project for surveillance of cancer and its associated factors: population-based and hospital-based registry" (VIGICAN), in the state of Mato Grosso (MT), Brazil. METHODS: VIGICAN was divided into two projects: a university extension one, which updated the data from the Population-based Cancer Registry (PBCR) of MT in the 2008-2016 period; and a research project, which collected primary data, through individual interviews and analysis of medical records of people with a diagnosis of cancer, aged 18 years or older, treated at reference hospitals for oncology. To analyze the factors associated with cancer, the following variables were collected: socioeconomic and demographic, social support, health status and behavior, and environmental exposure. RESULTS: In the 2008-2016 period, approximately one hundred thousand cases of cancer (incident and prevalent) were reported in the PBCR Cuiabá and PBCR Interior. After validation procedures, 50 thousand incident cases were elected. The survey interviewed 1,012 patients, 38.2% living in the municipalities of Cuiabá and Várzea Grande, 60.4% in small cities of the state, and 1.4% in other states. Preliminary data showed that the majority were women (55.0%) and younger than 60 years of age (54.3%). Among the interviewees, 7.2% reported smoking tobacco, 15.5% consumed alcoholic beverages (15.5%), and 32.7% lived nearby crops. CONCLUSION: The development of these projects allowed the integration of education with health services and will enable the recognition of specificities and different exposure scenarios and factors associated with cancer in the Mato Grosso territory.

Mortality trend of cancer and main types according to macroregion in the state of Mato Grosso, Brazil, 2000 to 2015.

OBJECTIVE: To describe the mortality trend from all cancers and the five main ones in the state of Mato Grosso, Brazil, from 2000 to 2015. METHODS: This is a descriptive, ecological, time series study, with data referring to deaths of residents of Mato Grosso due to cancer (ICD-10 codes C00 to C97), from the Mortality Information System (SIM). Time trend analyses of the standardized mortality rate from all cancers and five specific cancers (lung, prostate, breast, colorectal and cervical) for the state and according to macroregion (South, West, North, East and Center-North) were performed using linear regression (p<0.05). RESULTS: From 2000 to 2015, 28,525 deaths from all cancers in residents of the state of Mato Grosso were recorded. An increasing trend was observed for all cancers, in addition to lung, breast and colorectal cancers. The South and North macroregions showed an increasing trend for all cancers, breast and colorectal, and Center-North for breast and colorectal. East showed an increasing trend for all cancers, prostate and colorectal, and decreasing for cervical. CONCLUSION: In the state of Mato Grosso, there was an increasing trend in mortality for all cancers and from specific ones, with emphasis on breast and colorectal cancer in most macroregions.

Cancer mortality in the State of Mato Grosso from 2000 to 2015: temporal trend and regional differences.

OBJECTIVE: To analyze the trend of standardized cancer mortality rate in the state of Mato Grosso according to health regions, from 2000 to 2015. METHODS: Ecological time series study with data on deaths by cancer from the Mortality Information System. The rates were standardized using direct method and calculated by year and health regions. The annual percentage changes (APC) and respective confidence interval (95%CI) were obtained through simple linear regression. Thematic maps were built to show the spatial distribution of rates. RESULTS: There were 28,525 deaths by cancer registered in Mato Grosso, with the main types being lung, prostate, stomach, breast and liver cancer. The highest mortality rates were found in regions Médio Norte, Baixada Cuiabana and Sul Mato-Grossense. From 2000 to 2015, an upward trend was seen in the mortality rate by cancer in Mato Grosso (APC=0.81%; 95%CI 0.38-1.26), and in four health regions, Garças Araguaia (APC=2.27%; 95%CI 1.46-3.08), Sul Mato-Grossense (APC=1.12%; 95%CI 0.28-1.97), Teles Pires (APC=1.93%; 95%CI 0,11-3,74) and Vale dos Arinos (APC=2.61%; 95%CI 1.10-4.70), while the other regions remained stable. CONCLUSION: In the state of Mato Grosso and in the four health regions, cancer mortality rate showed a growing trend. The results point to the need to consider regional differences when thinking about actions for cancer prevention, control and assistance.

Socioeconomic development and colorectal cancer mortality in a state of the Brazilian Legal Amazon from 2005 to 2016.

OBJECTIVE: To analyze the correlation between colorectal cancer (CRC) mortality rates and socioeconomic factors in the five mesoregions (North, Northeast, Southeast, Southwest and Center-South) of the state of Mato Grosso, from 2005 to 2016. METHODS: Ecological study that considered deaths from CRC (C18 to C21) of residents of the state. Mortality rates were standardized by the direct method, using the world standard population. For the analysis of socioeconomic factors, the Firjan Municipal Development Index (IFDM) and its components (education, income and employment and health) were used. Means of mortality rates and socioeconomic factors between the mesoregions were tested using ANOVA, and Pearson's correlation coefficient was used to analyze the correlation between mortality rates due to CRC and these factors. RESULTS: In the period from 2005 to 2016, 1,492 deaths from CRC were registered in the state of Mato Grosso. The Southwest mesoregion had the highest average for both the crude rate and standardized CRC mortality rates (3.47 and 3.86 deaths/100,000 inhabitants, respectively). There was a significant correlation between mortality rates from the disease with the following indicators: Overall IFDM for the North, Southeast and Center-South mesoregions; education for the North and Southeast mesoregions; income and employment for the North and Center-South mesoregions; and health for the North, Southeast and Center-South mesoregions. CONCLUSION: There was a correlation between CRC mortality rates and better socioeconomic development in the state.

Trends in the incidence of colorectal cancer in Greater Cuiabá, Mato Grosso (Brazil), from 2000 to 2016.

OBJECTIVE: To analyze the temporal incidence trend of colorectal cancer (CRC), according to sex and age, in the Greater Cuiabá, Mato Grosso, Brazil, from 2000 to 2016. METHODS: Ecological time series study, with cases of CRC (C18 to C21) diagnosed from 2000 to 2016, of residents of the Greater Cuiabá (Cuiabá and Várzea Grande), in Mato Grosso. The information on the cases was obtained from the Population-Based Cancer Registry and population data from the Brazilian Institute of Geography and Statistics (IBGE). The rates were adjusted by world population. The age groups considered ranged from 30 to 39 years, 40 to 49 years, 50 to 59 years, 60 to 69 years, 70 to 79 years and 80 years and older. Joinpoint regression was used to analyze the trend of incidence. RESULTS: A total of 1,715 cases of CRC were registered with information on sex and age, with an adjusted rate of 16.4 new cases/100,000 men and 16.1 new cases/100,000 women. Men presented trend of increasing incidence rates in the age group of 70 to 79 years, with increase of 4.0% per year, while women presented trend of increase in the age group 50 to 59 years, with increase of 2.7% per year. CONCLUSION: Older men showed a more significant trend towards an increase in the incidence of CRC, but in women this occurred in a younger age group, highlighting the importance of considering age related information in the analyzes of occurrence of the disease in this population.

Cancer surveillance in Mato Grosso: methodological and operational aspects of a extension/research projects / Vigilância do câncer em Mato Grosso: aspectos metodológicos e operacionais de um projeto de extensão/pesquisa

Objective: To describe the methodological and operational aspects of the Cancer Surveillance Project and its associated factors: population-based and hospital-based registry (VIGICAN), in Mato Grosso (MT). Methods: VIGICAN was divided into two projects: an extension one, which updated the data from the Population-Based Cancer Registry (RCBP) of MT in the period 2008 to 2016; and one of research, which collected primary data, through individual interviews and analysis of medical records of people with a diagnosis of cancer, aged 18 years or over, treated at reference hospitals for oncology. To analyze the factors associated with cancer, the following variables were collected: socioeconomic and demographic, social support, status and health behavior, and environmental exposure. Results: In the períod from 2008 to 2016, approximately one hundred thousand cases of cancer (incident and prevalent) were reported in the RCBP Cuiabá and Interior. After validation procedures, fifty thousand incident cases were chosen. The survey interviewed 1,012 patients, 38.2% living in the municipalities of Cuiabá and Várzea Grande, 60.4% in the interior of the state and 1.4% in other states. Preliminary data revealed that the majority were female (55.0%) and younger than 60 years (54.3%). Among those interviewed, 7.2% reported smoking tobacco, 15.5% consumed alcoholic beverages (15.5%) and 32.7% lived close to crops. Conclusion: The development of these projects allowed the integration of education with health services and will enable the recognition of specificities and different exposure scenarios and factors associated with cancer in the Mato Grosso territory.

Objetivo: Descrever os aspectos metodológicos e operacionais do Projeto Vigilância do Câncer e seus fatores associados: registro de base populacional e hospitalar (VIGICAN), em Mato Grosso (MT). Métodos: O VIGICAN se desdobrou em dois projetos: um de extensão, que atualizou os dados dos Registros de Câncer de Base Populacional (RCBP) de MT no período de 2008 a 2016; e um de pesquisa, que coletou dados primários, por meio de entrevistas individuais e análise de prontuários de pessoas com diagnóstico de câncer, com 18 anos ou mais, atendidas em hospitais de referência para oncologia. Para analisar os fatores associados ao câncer, foram coletadas as seguintes variáveis: socioeconômicas e demográficas, suporte social, situação e comportamentos de saúde e exposição ambiental. Resultados: No período de 2008 a 2016, foram notificados nos RCBP Cuiabá e Interior, aproximadamente, 100 mil casos de câncer (incidentes e prevalentes). Após procedimentos de validação, foram eleitos 50 mil casos incidentes. A pesquisa entrevistou 1.012 pacientes, sendo 38,2% residentes nos municípios de Cuiabá e Várzea Grande, 60,4% no interior do estado e 1,4% em outros estados. Os dados preliminares revelaram que a maioria era do sexo feminino (55,0%) e tinha menos de 60 anos (54,3%). Entre os entrevistados, 7,2% relataram fumar tabaco, 15,5% consumiam bebidas alcoólicas (15,5%) e 32,7% moravam próximos a lavouras. Conclusão: O desenvolvimento desses projetos permitiu a integração do ensino com os serviços de saúde e possibilitará o reconhecimento das especificidades e diferentes cenários de exposição e fatores associados ao câncer do território mato-grossense.

Mortality trend of cancer and main types by macrorregions of the state of Mato Grosso, Brazil, 2000 to 2015 / Tendência da mortalidade por câncer e principais tipos, segundo macrorregiões do Estado de Mato Grosso, 2000 a 2015

Objective: To describe the mortality trend from all causes of cancer and the five main causes in the state of Mato Grosso, Brazil, from 2000 to 2015. Methods: This is a descriptive, ecological, time series study, with data referring to deaths of residents of Mato Grosso due to neoplasms (ICD-10 codes C00 to C97), from the Mortality Information System (SIM). Time trend analyzes of the standardized mortality rate from all causes of cancer and five specific causes of cancer (lung, prostate, breast, colorectal and cervix) for the state and according to macroregions (South, West, North, East and Center -North) were performed using linear regression (p-value<0.05). Results: From 2000 to 2015, 28,525 deaths from all causes of cancer in residents of the state of Mato Grosso were recorded. An increasing trend was observed for all causes of cancer, in addition to lung, breast and colorectal cancers. Southern and Northern macroregions showed an increasing trend for all causes, breast and colorectal; North-Central for breast and colorectal. East was increasing for all causes, prostate and colorectal, and decreasing for cervix. Conclusions: In the state of Mato Grosso, there was an increasing trend in mortality from all causes of cancer and from specific causes, with emphasis on breast and colorectal cancer in most macroregions.

Objetivo: Descrever a tendência da mortalidade por todas as causas de câncer e das cinco principais causas no Estado de Mato Grosso, Brasil, no período 2000 a 2015. Métodos: Trata-se de um estudo descritivo, ecológico, do tipo série temporal, com dados referentes aos óbitos de residentes de Mato Grosso por neoplasias (códigos C00 a C97 da CID-10), provenientes do Sistema de Informações sobre Mortalidade (SIM). A tendência temporal da taxa de mortalidade padronizada de todas as causas de câncer e cinco causas específicas de câncer (pulmão, próstata, mama feminina, colorretal e colo do útero) para o estado e segundo macrorregiões (Sul, Oeste, Norte, Leste e Centro-Norte) foi analisada por meio de regressão linear (p-valor<0,05). Resultados: De 2000 a 2015, ocorreram 28.525 óbitos por todas as causas de câncer em residentes no Estado de Mato Grosso. Tendência crescente foi observada para todas as causas de câncer, além dos cânceres de pulmão, mama e colorretal. Macrorregiões Sul e Norte apresentaram tendência crescente para todas as causas, mama e colorretal; Centro-Norte para mama e colorretal. Na Macrorregião Leste foi crescente para todas as causas, próstata e colorretal, e decrescente para colo do útero. Conclusões: No Estado de Mato Grosso, verificou-se tendência crescente da mortalidade por todas as causas de câncer e por causas específicas, com destaque para mama e colorretal na maioria das macrorregiões.

Socioeconomic development and colorectal cancer mortality in a federative unit of the Legal Amazon, from 2005 to 2016 / Desenvolvimento socioeconômico e mortalidade por câncer colorretal em uma unidade federativa da Amazônia Legal, de 2005 a 2016

Objective: To analyze the correlation between colorectal cancer (CRC) mortality rates and socioeconomic factors in the five mesoregions (North, Northeast, Southeast, Southwest and Center-South) of the state of Mato Grosso, from 2005 to 2016. Methods: Ecological study, which considered deaths from CRC (C18 to C21) of residents of the state. Mortality rates were standardized by the direct method, using the world standard population. For the analysis of socioeconomic factors, the Firjan Municipal Development Index (IFDM) and its components (Education, Income and employment; Health) were used. Means of mortality rates and socioeconomic factors between the mesoregions were tested using ANOVA, and Pearson's correlation coefficient was used to analyze the correlation between mortality rates due to CRC and these factors. Results: In the period from 2005 to 2016, 1,492 deaths from CRC were registered in the state of Mato Grosso. The mesoregion with the highest average of both the crude rate and the standardized rate of mortality from CRC was the Southwest (3.47 and 3.86 deaths/100 thousand inhab.). There was a significant correlation between mortality rates from the disease with the following indicators: General IFDM for the North, Southeast and Center-South mesoregions; Education for the North and Southeast mesoregions; Income and employment for the North and Center-South mesoregions and Health for the North, Southeast and Center-South mesoregions. Conclusion: There was correlation between the CRC mortality rates and better socioeconomic development in the state.

Objetivo: Analisar a correlação entre as taxas de mortalidade por câncer colorretal (CCR) e os fatores socioeconômicos nas cinco mesorregiões (Norte, Nordeste, Sudeste, Sudoeste e Centro-Sul) do estado de Mato Grosso, de 2005 a 2016. Métodos: Estudo ecológico, que considerou os óbitos por CCR (C18 a C21) de residentes do Estado. As taxas de mortalidade foram padronizadas pelo método direto, utilizando-se a população padrão mundial. Para a análise dos fatores socioeconômicos foi utilizado o Índice Firjan de Desenvolvimento Municipal Geral (IFDM) e seus componentes (Educação; Renda e emprego; Saúde). Foram testadas as médias das taxas de mortalidade e dos fatores socioeconômicos entre as mesorregiões por meio da ANOVA, e empregado o coeficiente de correlação de Pearson para análise da correlação entre as taxas de mortalidade por CCR e esses fatores. Resultados: No período de 2005 a 2016, foram registrados 1.492 óbitos por CCR no estado de Mato Grosso. A mesorregião com a maior média tanto da taxa bruta quanto da taxa padronizada de mortalidade por CCR foi a Sudoeste (3,47 e 3,86 óbitos/100 mil hab.). Houve correlação significante entre as taxas de mortalidade por CCR com os seguintes indicadores: IFDM Geral para as mesorregiões Norte, Sudeste e Centro-Sul; Educação para as mesorregiões Norte e Sudeste; Renda e emprego para as mesorregiões Norte e Centro-Sul e Saúde para as mesorregiões Norte, Sudeste e Centro-Sul. Conclusão: Houve correlação da taxa de mortalidade de CCR com melhor desenvolvimento socioeconômico no estado.

Cancer mortality in the state of Mato Grosso from 2000 to 2015: temporal trend and regional differences / Mortalidade por câncer no Estado de Mato Grosso no período de 2000 a 2015: tendência temporal e diferenças regionais

Objective: To analyze the trend of standardized rate due to mortality by cancer in the state of Mato Grosso, according to health regions, from 2000 to 2015. Methods: Ecological study of time series with data on deaths by cancer from the Mortality Information System. The rates were standardized using direct method and calculated by year and health regions. The annual percentage change (APC) and its respective confidence interval (CI 95%) were obtained through simple linear regression. Thematic maps were built to describe the rates spatial distribution. Results: There were 28,525 deaths by cancer registered in Mato Grosso and the five main causes were lung, prostate, stomach, breast and liver cancer. The highest mortality rates were found in the Médio Norte, Baixada Cuiabana and Sul Matogrossense regions. From 2000 to 2015 a growing trend was observed in the mortality rate by cancer in Mato Grosso (APC=0.81%; CI95%: 0.38; 1.26), and in four health regions, Garças Araguaia (APC=2.27%; CI95%: 1.46; 3.08), Sul Matogrossense (APC=1.12%; CI95%: 0.28; 1.97), Teles Pires (APC=1.93%; IC95%: 0,11; 3,74) and Vale dos Arinos (APC=2.61%; CI95%: 1.10; 4.70), the oter regions presented stability. Conclusion: In the state of Mato Grosso and in the four health regions there was verified a growing trend of mortality due to cancer. The results indicate the need to consider the regional differences regarding actions for cancer prevention, control and assistance.

Objetivo: Analisar a tendência da taxa padronizada de mortalidade por câncer no Estado de Mato Grosso, conforme regiões de saúde, no período de 2000 a 2015. Métodos: Estudo ecológico de séries temporais com dados de óbitos por neoplasias do Sistema de Informações de Mortalidade. As taxas foram padronizadas pelo método direto e calculadas por ano e por regiões de saúde. A variação anual percentual (annual percent change ­ APC) e seu respectivo intervalo de 95% de confiança (IC 95%) foram obtidos por meio da regressão linear simples. Foram construídos mapas temáticos para descrever a distribuição espacial das taxas. Resultados: Foram registrados 28.525 óbitos por câncer em Mato Grosso e os cinco principais tipos de câncer foram de pulmão, próstata, estomago, mama e fígado. As maiores taxas de mortalidade foram encontradas nas regiões Médio Norte, Baixada Cuiabana e Sul Matogrossense. No período de 2000 a 2015 foi observada tendência crescente na taxa de mortalidade por câncer em Mato Grosso (APC=0,81%; IC95%: 0,38; 1,26), e em quatro regiões de saúde, Garças Araguaia (APC=2,27%; IC95%: 1,46; 3,08), Sul Matogrossense (APC=1,12%; IC95%: 0,28; 1,97), Teles Pires (APC=1,93%; IC95%: 0,11; 3,74) e Vale dos Arinos (APC=2,61%; IC95%: 1,10; 4,70), as demais regiões apresentaram estabilidade. Conclusão: No Estado de Mato Grosso e em quatro regiões de saúde foi verificada tendência crescente de mortalidade por câncer. Os resultados indicam a necessidade de se considerar as diferenças regionais para as ações de prevenção, controle e assistência ao câncer.

Trends in colorectal cancer incidence in Grande Cuiabá, Mato Grosso (Brazil), from 2000 to 2016 / Tendência da incidência de câncer colorretal na Grande Cuiabá, Mato Grosso (Brasil), de 2000 a 2016

Objective: To analyze the temporal trend of incidence of colorectal cancer (CRC), according to sex and age, in Greater Cuiabá, Mato Grosso, Brazil, from 2000 to 2016. Methods: Ecological time series study, with cases of CRC (C18 to C21) diagnosed from 2000 to 2016, of residents of Greater Cuiabá (Cuiabá and Várzea Grande), in Mato Grosso. Information on the cases was obtained from the Population-Based Cancer Registry and population data from IBGE. Rates were adjusted by world population. The age groups from 30 to 39 years old, 40 to 49 years old, 50 to 59 years old, 60 to 69 years old, 70 to 79 years old and 80 years old or more were considered. To analyze the trend of incidence, the Joinpoint regression was used. Results: A total of 1,715 cases of CCR were registered with information on sex and age, with an adjusted rate of 16.4 new cases/100,000 men and 16.1 new cases/100,000 women. Men presented trend of increasing incidence rates in the age group of 70 to 79 years, with increase of 4.0% per year, while women presented trend of increase in the age group 50 to 59 years, with increase of 2.7% per year. Conclusion: Older men showed more significant trend towards an increase in the incidence of CRC, but in women this occurred in a younger age group, highlighting the importance of considering information about age in the analyzes of the occurrence of the disease in this population.

Objetivo: Analisar a tendência temporal da incidência do câncer colorretal (CCR), segundo sexo e faixa etária, na Grande Cuiabá, Mato Grosso (Brasil), de 2000 a 2016. Métodos: Estudo ecológico de séries temporais, com casos de CCR (C18 a C21) diagnosticados de 2000 a 2016, de residentes da Grande Cuiabá (Cuiabá e Várzea Grande), em Mato Grosso. As informações dos casos foram provenientes do Registro de Câncer de Base Populacional e os dados populacionais do IBGE. As taxas foram ajustadas pela população mundial. Considerou-se as faixas etárias de 30 a 39 anos, 40 a 49 anos, 50 a 59 anos, 60 a 69 anos, 70 a 79 anos e 80 anos ou mais. Para análise da tendência temporal da incidência, empregou-se a regressão por Joinpoint. Resultados: Foram registrados 1.715 casos de CCR com informação de sexo e idade, com taxa ajustada de 16,4 casos novos/100.000 homens e 16,1 casos novos/100.000 mulheres. Os homens apresentaram tendência temporal de aumento das taxas de incidência na faixa etária de 70 a 79 anos, com acréscimo de 4,0% ao ano, e as mulheres apresentaram tendência temporal de aumento na faixa etária de 50 a 59 anos, com acréscimo de 2,7% ao ano. Conclusão: Os homens mais velhos apresentaram tendência temporal de aumento da incidência de CCR de forma mais expressiva, porém nas mulheres isso ocorreu em faixa etária mais jovem, ressaltando a importância de considerar a informação sobre a idade nas análises sobre a ocorrência da doença nessa população.

Space-time clusters of severe acute respiratory syndrome and COVID-19 and hierarchical urban network in the state of Mato Grosso, Brazil, 2020-2021 / Clusters espaço-temporais de síndrome respiratória aguda grave e COVID-19 e rede urbana hierárquica no estado de Mato Grosso, Brasil, 2020-2021 / Agrupaciones espacio-temporales de síndrome respiratorio agudo severo y COVID-19 y red urbana jerárquica en el estado de Mato Grosso, Brasil, 2020-2021

Objective: to analyze the space-time distribution of COVID-19 in the state of Mato Grosso, Brazil. Methods: Weekly case records of Severe Acute Respiratory Syndrome were obtained from the Ministry of Health's Database related to this syndrome, including data from COVID-19. Temporal and spatiotemporal analysis using scanning statistics to identify clusters of severe acute respiratory syndrome cases were performed with the software SaTScan. Results: A total of 27,093 cases was observed, with an incidence of 768.33/100,000 inhabitants. The spatial distribution considering the period of study evidenced the heterogeneity of values in the state. The highest incidence rates were observed in more populous municipalities. Conclusion: We highlight priority areas for interventions, aiming at controlling the transmission of the disease and reducing transmission risks to more remote areas of the state of Mato Grosso.

Objetivo: Analisar distribuição espaço-temporal de COVID-19 no estado de Mato Grosso, Brasil. Métodos: Registros de casos semanais de Síndrome Respiratória Aguda Grave foram obtidos junto ao Banco de Dados dessa síndrome do Ministério da Saúde, incluindo dados de COVID-19. Análises temporal e espaço-temporal utilizando varreduras estatísticas para identificação de clusters de casos de síndrome respiratória aguda grave foram realizadas com o programa SaTScan. Resultados: Foram observados 27.093 casos, com incidência de 768,33/100.000 habitantes. A distribuição espacial considerando o período de estudo evidenciou heterogeneidade de valores no estado. As maiores taxas de incidência foram observadas em municípios mais populosos. Conclusão: Destacam-se áreas prioritárias para intervenções, priorizando controle da transmissão da doença e redução dos riscos de transmissão para áreas mais remotas do estado de Mato Grosso.

Objetivo: Analizar la distribución espacio-temporal de COVID-19 en la provincia estado de Mato Grosso, Brasil. Métodos: Se obtuvieron registros semanales de casos de Síndrome Respiratorio Agudo Severo (SRAG) de la Base de Datos SRAG del Ministerio de Salud, incluyendo datos de COVID-19. Se realizaron análisis temporales y espaciotemporales utilizando exploraciones estadísticas para identificar grupos de casos SRAG con el programa SaTScan. Resultados: se observaron 27.093 casos, con una incidencia de 768,33 / 100.000 habitantes. La distribución espacial considerando el período de estudio mostró heterogeneidad de valores en el estado. Las tasas de incidencia más altas se observaron en los municipios más poblados. Conclusión: Se destacan las áreas prioritarias para las intervenciones, priorizando el control de la transmisión de enfermedades y la reducción de los riesgos de transmisión a áreas más remotas del estado de Mato Grosso.

Trends in the incidence of colorectal cancer in Greater Cuiabá, Mato Grosso (Brazil), from 2000 to 2016 / Tendência da incidência de câncer colorretal na Grande Cuiabá, Mato Grosso (Brasil), de 2000 a 2016

ABSTRACT: Objective: To analyze the temporal incidence trend of colorectal cancer (CRC), according to sex and age, in the Greater Cuiabá, Mato Grosso, Brazil, from 2000 to 2016. Methods: Ecological time series study, with cases of CRC (C18 to C21) diagnosed from 2000 to 2016, of residents of the Greater Cuiabá (Cuiabá and Várzea Grande), in Mato Grosso. The information on the cases was obtained from the Population-Based Cancer Registry and population data from the Brazilian Institute of Geography and Statistics (IBGE). The rates were adjusted by world population. The age groups considered ranged from 30 to 39 years, 40 to 49 years, 50 to 59 years, 60 to 69 years, 70 to 79 years and 80 years and older. Joinpoint regression was used to analyze the trend of incidence. Results: A total of 1,715 cases of CRC were registered with information on sex and age, with an adjusted rate of 16.4 new cases/100,000 men and 16.1 new cases/100,000 women. Men presented trend of increasing incidence rates in the age group of 70 to 79 years, with increase of 4.0% per year, while women presented trend of increase in the age group 50 to 59 years, with increase of 2.7% per year. Conclusion: Older men showed a more significant trend towards an increase in the incidence of CRC, but in women this occurred in a younger age group, highlighting the importance of considering age related information in the analyzes of occurrence of the disease in this population.

RESUMO: Objetivo: Analisar a tendência temporal da incidência do câncer colorretal (CCR) segundo sexo e faixa etária, na Grande Cuiabá, Mato Grosso (Brasil), de 2000 a 2016. Métodos: Estudo ecológico de séries temporais, com casos de CCR (C18 a C21) diagnosticados de 2000 a 2016 em residentes da Grande Cuiabá (Cuiabá e Várzea Grande), em Mato Grosso. As informações dos casos foram provenientes do Registro de Câncer de Base Populacional e os dados populacionais do Instituto Brasileiro de Geografia e Estatística. As taxas foram ajustadas pela população mundial. Consideraram-se as faixas etárias de 30 a 39 anos, 40 a 49 anos, 50 a 59 anos, 60 a 69 anos, 70 a 79 anos e 80 anos ou mais. Para análise da tendência temporal da incidência, empregou-se a regressão por joinpoint. Resultados: Foram registrados 1.715 casos de CCR com informação de sexo e idade, com taxa ajustada de 16,4 casos novos/100 mil homens e 16,1 casos novos/100 mil mulheres. Os homens apresentaram tendência temporal de aumento das taxas de incidência na faixa etária de 70 a 79 anos, com acréscimo de 4,0% ao ano, e as mulheres apresentaram tendência temporal de aumento na faixa etária de 50 a 59 anos, com acréscimo de 2,7% ao ano. Conclusão: Os homens mais velhos apresentaram tendência temporal de aumento da incidência de CCR de forma mais expressiva, porém nas mulheres isso ocorreu em faixa etária mais jovem, ressaltando a importância de considerar a informação sobre a idade nas análises sobre a ocorrência da doença nessa população.

Cancer surveillance in Mato Grosso, Brazil: methodological and operational aspects of a university extension/research project / Vigilância do câncer em Mato Grosso, Brasil: aspectos metodológicos e operacionais de um projeto de extensão/pesquisa

ABSTRACT: Objective: To describe the methodological and operational aspects of the "Project for surveillance of cancer and its associated factors: population-based and hospital-based registry" (VIGICAN), in the state of Mato Grosso (MT), Brazil. Methods: VIGICAN was divided into two projects: a university extension one, which updated the data from the Population-based Cancer Registry (PBCR) of MT in the 2008-2016 period; and a research project, which collected primary data, through individual interviews and analysis of medical records of people with a diagnosis of cancer, aged 18 years or older, treated at reference hospitals for oncology. To analyze the factors associated with cancer, the following variables were collected: socioeconomic and demographic, social support, health status and behavior, and environmental exposure. Results: In the 2008-2016 period, approximately one hundred thousand cases of cancer (incident and prevalent) were reported in the PBCR Cuiabá and PBCR Interior. After validation procedures, 50 thousand incident cases were elected. The survey interviewed 1,012 patients, 38.2% living in the municipalities of Cuiabá and Várzea Grande, 60.4% in small cities of the state, and 1.4% in other states. Preliminary data showed that the majority were women (55.0%) and younger than 60 years of age (54.3%). Among the interviewees, 7.2% reported smoking tobacco, 15.5% consumed alcoholic beverages (15.5%), and 32.7% lived nearby crops. Conclusion: The development of these projects allowed the integration of education with health services and will enable the recognition of specificities and different exposure scenarios and factors associated with cancer in the Mato Grosso territory.

RESUMO: Objetivo: Descrever os aspectos metodológicos e operacionais do projeto "Vigilância do câncer e seus fatores associados: registro de base populacional e hospitalar" (VIGICAN), em Mato Grosso (MT). Métodos: O VIGICAN desdobrou-se em dois projetos: um de extensão, que atualizou os dados dos Registros de Câncer de Base Populacional (RCBP) de Mato Grosso no período de 2008 a 2016; e um de pesquisa, que coletou dados primários por meio de entrevistas individuais e análise de prontuários de pessoas com diagnóstico de câncer, com 18 anos ou mais, atendidas em hospitais de referência para oncologia. Para analisar os fatores associados ao câncer, foram coletadas as seguintes variáveis: socioeconômicas e demográficas, suporte social, situação e comportamentos de saúde e exposição ambiental. Resultados: No período de 2008 a 2016, foram notificados nos RCBP Cuiabá e Interior, aproximadamente, 100 mil casos de câncer (incidentes e prevalentes). Após os procedimentos de validação, foram eleitos 50 mil casos incidentes. A pesquisa entrevistou 1.012 pacientes, sendo 38,2% residentes nos municípios de Cuiabá e Várzea Grande, 60,4% no interior do Estado e 1,4% em outros Estados. Os dados preliminares revelaram que a maioria era do sexo feminino (55,0%) e tinha menos de 60 anos (54,3%). Entre os entrevistados, 7,2% relataram fumar tabaco, 15,5% consumiam bebidas alcoólicas (15,5%) e 32,7% moravam próximo a lavouras. Conclusão: O desenvolvimento desses projetos permitiu a integração do ensino com os serviços de saúde e possibilitará o reconhecimento das especificidades e dos diferentes cenários de exposição ao câncer, bem como fatores associados a ele, no território mato-grossense.

Mortality trend of cancer and main types according to macroregion in the state of Mato Grosso, Brazil, 2000 to 2015 / Tendência da mortalidade por câncer e principais tipos segundo macrorregiões do Estado de Mato Grosso, 2000 a 2015

ABSTRACT: Objective: To describe the mortality trend from all cancers and the five main ones in the state of Mato Grosso, Brazil, from 2000 to 2015. Methods: This is a descriptive, ecological, time series study, with data referring to deaths of residents of Mato Grosso due to cancer (ICD-10 codes C00 to C97), from the Mortality Information System (SIM). Time trend analyses of the standardized mortality rate from all cancers and five specific cancers (lung, prostate, breast, colorectal and cervical) for the state and according to macroregion (South, West, North, East and Center-North) were performed using linear regression (p<0.05). Results: From 2000 to 2015, 28,525 deaths from all cancers in residents of the state of Mato Grosso were recorded. An increasing trend was observed for all cancers, in addition to lung, breast and colorectal cancers. The South and North macroregions showed an increasing trend for all cancers, breast and colorectal, and Center-North for breast and colorectal. East showed an increasing trend for all cancers, prostate and colorectal, and decreasing for cervical. Conclusion: In the state of Mato Grosso, there was an increasing trend in mortality for all cancers and from specific ones, with emphasis on breast and colorectal cancer in most macroregions.

RESUMO: Objetivo: Descrever a tendência da mortalidade por todas as causas de câncer e as cinco principais causas no Estado de Mato Grosso, Brasil, no período de 2000 a 2015. Métodos: Trata-se de um estudo descritivo, ecológico, do tipo série temporal, com dados referentes aos óbitos de residentes de Mato Grosso por neoplasias (códigos C00 a C97 da Classificação Internacional de Doenças — CID-10), provenientes do Sistema de Informações sobre Mortalidade. A tendência temporal da taxa de mortalidade padronizada de todas as causas de câncer e de cinco causas específicas (pulmão, próstata, mama feminina, colorretal e colo do útero) para o Estado e segundo macrorregiões (Sul, Oeste, Norte, Leste e Centro-Norte) foi analisada por meio de regressão linear (p<0,05). Resultados: De 2000 a 2015, ocorreram 28.525 óbitos por todas as causas de câncer em residentes do Estado de Mato Grosso. Tendência crescente foi observada para todas as causas de câncer, além dos cânceres de pulmão, mama e colorretal. As macrorregiões Sul e Norte apresentaram tendência crescente para todas as causas, mama e colorretal; Centro-Norte para mama e colorretal; Leste foi crescente para todas as causas, próstata e colorretal e decrescente para colo do útero. Conclusão: No Estado de Mato Grosso, verificou-se tendência crescente de mortalidade por todas as causas de câncer e por causas específicas, com destaque para mama e colorretal na maioria das macrorregiões.

Cancer mortality in the State of Mato Grosso from 2000 to 2015: temporal trend and regional differences / Mortalidade por câncer no estado de Mato Grosso, Brasil, no período de 2000 a 2015: tendência temporal e diferenças regionais

ABSTRACT: Objective: To analyze the trend of standardized cancer mortality rate in the state of Mato Grosso according to health regions, from 2000 to 2015. Methods: Ecological time series study with data on deaths by cancer from the Mortality Information System. The rates were standardized using direct method and calculated by year and health regions. The annual percentage changes (APC) and respective confidence interval (95%CI) were obtained through simple linear regression. Thematic maps were built to show the spatial distribution of rates. Results: There were 28,525 deaths by cancer registered in Mato Grosso, with the main types being lung, prostate, stomach, breast and liver cancer. The highest mortality rates were found in regions Médio Norte, Baixada Cuiabana and Sul Mato-Grossense. From 2000 to 2015, an upward trend was seen in the mortality rate by cancer in Mato Grosso (APC=0.81%; 95%CI 0.38-1.26), and in four health regions, Garças Araguaia (APC=2.27%; 95%CI 1.46-3.08), Sul Mato-Grossense (APC=1.12%; 95%CI 0.28-1.97), Teles Pires (APC=1.93%; 95%CI 0,11-3,74) and Vale dos Arinos (APC=2.61%; 95%CI 1.10-4.70), while the other regions remained stable. Conclusion: In the state of Mato Grosso and in the four health regions, cancer mortality rate showed a growing trend. The results point to the need to consider regional differences when thinking about actions for cancer prevention, control and assistance.

RESUMO: Objetivo: Analisar a tendência da taxa padronizada de mortalidade por câncer no estado de Mato Grosso, Brasil, conforme regiões de saúde, no período de 2000 a 2015. Métodos: Estudo ecológico de séries temporais com dados de óbitos por neoplasias do Sistema de Informação sobre Mortalidade. As taxas foram padronizadas pelo método direto e calculadas por ano e por regiões de saúde. A variação anual percentual (annual percent change — APC) e seu respectivo intervalo de 95% de confiança (IC95%) foram obtidos por meio da regressão linear simples. Construíram-se mapas temáticos para descrever a distribuição espacial das taxas. Resultados: Foram registrados 28.525 óbitos por câncer em Mato Grosso, e os cinco principais tipos de câncer foram de pulmão, próstata, estômago, mama e fígado. As maiores taxas de mortalidade foram encontradas nas regiões Médio Norte, Baixada Cuiabana e Sul-Mato-Grossense. No período de 2000 a 2015 foi observada tendência crescente na taxa de mortalidade por câncer em Mato Grosso (APC=0,81%; IC95% 0,38-1,26), e em quatro regiões de saúde, Garças Araguaia (APC=2,27%; IC95% 1,46-3,08), Sul-Mato-Grossense (APC=1,12%; IC95% 0,28-1,97), Teles Pires (APC=1,93%; IC95% 0,11-3,74) e Vale dos Arinos (APC=2,61%; IC95% 1,10-4,70). As demais regiões apresentaram estabilidade. Conclusão: No estado de Mato Grosso e em quatro regiões de saúde foi verificada tendência crescente de mortalidade por câncer. Os resultados indicam a necessidade de se considerar as diferenças regionais para as ações de prevenção e assistência ao câncer e de controle.